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Home – Child Mental Health Blog

Prescribing Exercise

Posted: March 26th, 2012 by David Rettew

By Eliza Pillard, LiCSW

One of the most important components to our Family Based Treatment Approach to child psychiatric issues here at the VCCYF is to “prescribe” our patients engagement in physical activity. Often this takes the form of recommending that a child be enrolled in a team sport, ideally every season.  For some families this comes naturally and they only need a reminder to make exercise and sports participation a priority.  For other families, especially when the adults themselves are not active, having their child participate in a team sport can seem unnecessary or daunting.  In this case helping caregivers understand the benefits of physical exercise not only for the designated patient, but for the adults as well, can have a profound effect on the family culture.  I recently reviewed this 9 minute video:  23 and 1/2 hours: what is the single most important thing for your health?  (spoiler alert!) regarding the benefits of exercise. The video was created by Mike Evans, MD, a family physician at St. Michael’s Hospital and an Associate Professor of Family Medicine and Public Health at the University of Toronto. The video uses an animated white board technique and is filled with compelling and accessible evidence regarding the health and mental health benefits of daily exercise.

If recommending physical activity as an intervention to improve a child’s mental health is falling on deaf ears, perhaps “prescribing” that a family view this video together would be a reasonable next step.

To read more about Dr. Evan’s work and to view other health related videos/articles go to: http://www.myfavouritemedicine.com/about-dr-mike/

References:

Hudziak, JJ.,& Bartels, M. (2008): Genetic and Environmental Influences on Wellness, Resilience, and Psychopathology: A family-based approach for promotion, prevention, and intervention. In Hudziak, JJ Editor, Developmental Psychopathology and Wellness: Genetic and environmental influences (first edition, pp. 267-282).Arlington, VA: American Psychiatric Publishing, Inc. 

A Teen’s Brain: Driving Without the Breaks

Posted: March 19th, 2012 by David Rettew

by David Fassler, MD

Clinical Professor of Psychiatry, UVM College of Medicine

The following was previously posted in a blog for Scientific American and adapted for this blog.

The next time a teenager behaves inexplicably, remember: his brain is like a car without brakes. The more primitive parts of the brain are well developed, acting like a powerful accelerator encouraging teens to take risks, act on impulse and seek novel experiences. But the areas that control planning and reasoning have not yet matured. As a result, teens are less likely to stop, think things through, modify their behavior or fully consider the consequences of their actions.

Dr. Fassler, testifying in Nevada

On March 20, the U.S. Supreme Court will hear two cases, Jackson v. Hobbs and Miller v. Alabama, concerning teenagers who have committed homicide offenses. The Court will consider whether they should be eligible for sentences of life in prison without the possibility of parole. The medical and mental health community have been following these cases closely, and providing input to the Court on the science of adolescent brain development. The American Medical Association, the American Academy of Child and Adolescent Psychiatry, the American Psychological Association and the American Psychiatric Association, among others, have filed amicus briefs emphasizing just how different teen brains are from those of adults.

What we know

In the 1970s, it was widely assumed that brain development was essentially complete by the age of three. Today, we know this is far from the case. The brain continues to mature and develop throughout adolescence and even into early adulthood. The teenage years, in particular, are a very active and important time for brain development.

During adolescence, there is a rapid increase in the interconnections between the brain cells. Gray matter grows, followed by a refinement, or “pruning,” of the connections and pathways. We also see an increase in the white matter, or myelin. The myelin acts as an insulator and enhances communication at the cellular level. It is essential for coordinated thought, action and behavior.

The instinctual parts of the brain develop first followed by the regions that control reasoning and help us think before we act. Specifically, the amygdala, which is a more primitive part of the brain responsible for gut reactions, including fear and aggressive behaviors, develops before more advanced areas like the frontal lobes, which help us control our impulses, emotions and responses.

Research has shown that adolescents actually use their brains differently than adults when attempting to reason, solve problems, or deal with stressful situations. For example, they tend to rely more on these instinctual structures, like the amygdala, and less on the more advanced areas, like the frontal lobes, which are associated with more goal-oriented and rational thinking.

Teenagers are less likely to use the part of the brain that asks “’Is this a good idea? What is the consequence of this action?’ It’s not that they don’t have a frontal lobe. But they’re going to access it more slowly,” Frances Jensen, a pediatric neurologist at Children’s Hospital in Boston, recently explained on National Public Radio.

Research has also identified at least two other areas of the brain that undergo significant growth and development during adolescence. These are the corpus callosum, which connects the two halves, or hemispheres, of the brain, and the cerebellum, which is located at the base of the brain.

The corpus callosum, which creates a pathway from one side of the brain to the other, facilitates problem solving. The cerebellum primarily controls physical coordination and movement, but also helps organize our thought processes. All of these anatomical structures — the amygdala, the frontal lobes, the corpus callosum, and the cerebellum — are physically changing and maturing throughout adolescence.

Based on the stage of their brain development, teenagers are more likely to act on impulse, misread social cues and others’ emotions, get into fights and accidents, or engage in more serious risk-taking behavior, like driving recklessly or while intoxicated. Because adolescents are less likely than adults to think before they act, every state has laws restricting them from activities that require mature judgment, including voting, serving on juries and purchasing alcohol.

In 2005, the Supreme Court cited scientific studies when it struck down the death penalty for people under the age of eighteen. The Justices relied on similar reasoning in 2010 when they abolished sentences of life without parole for juveniles convicted of non-homicide offenses. Hopefully, their consideration of these new cases will once again be informed by the scientific data and our contemporary understanding of adolescent brain development.

Does Cannabis Cause Psychosis?

Posted: March 14th, 2012 by David Rettew

Cannabis use in Vermont youth is extremely high with about a quarter of 11th and 12th graders having used it in the last 30 days, according to the Vermont Youth Risk Behavior Survey.  While cannabis is still considered to be relatively harmless by many, the health risks associated with its use are becoming increasingly apparent, especially as the THC potency has been increasing.  

As described in a recent edition of Psychiatric Times, one such danger that has been noticed by researchers is psychosis and schizophrenia. The amount of increased risk varies by study, but a 40% increased risk among users which rises to 200% and more for those who smoke regularly has been found in many reports.   Given that the base rate of psychotic illness is not that low, this increased risk translates into a large number of youth who can progress to severe disability. These symptoms often don’t remit when the cannabis use stops.  The risk may be higher for individuals who begin smoking in adolescence and has been found to be related to specific genetic vulnerabilities, as documented in the well known study from New Zealand that showed that cannabis users who had the Val/Val or Val/Met genotype at the Val158Met functional polymorphism of the COMT gene were at especially high risk.  Many of the studies have some methodological complications, however, that limit firmer conclusions.

A recent meta-analysis also published a surprising finding that individuals with schizophrenia had improved cognitive functioning if they had a history of a cannabis use disorder.  However, some have argued that the cannabis use group contains people who would not have developed schizophrenia otherwise and may have a less severe course than those the non-user group who came to their diagnosis through other means. 

Will the prospect of possibly developing schizophrenia deter some adolescents from using cannabis?  While many will likely remain unconvinced, this risk should certainly be part of an important conversation to have with our adolescent patients. 

References:

Caspi A, Moffitt TE, Cannon M, et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry. 2005;57:1117-1127.

Rabin RA, Zakzanis KK, George TP. The effects of cannabis use on neurocognition in schizophrenia: a meta-analysis. Schizophr Res. 2011;128:111-116.

Who Should Evaluate and Treat ADHD? The AAP’s Nudge

Posted: March 7th, 2012 by David Rettew

In October, the journal Pediatrics, based right here in Vermont, published updated guidelines from the American Academy of Pediatrics (AAP) regarding the assessment and treatment of ADHD.  

Since its publication, what has clearly generated the most media discussion about these new guidelines is the inclusion of preschool children (age 4 and above) in the recommendations.  The authors state that behavioral therapy should be the first line of treatment in preschoolers with ADHD, but their inclusion at all in the assessment and treatment recommendations has been problematic to some.   

Perhaps overshadowed by the attention (no pun intended) paid to preschool ADHD is the position of the AAP that the diagnosis and treatment of ADHD, and other potential psychiatric comorbidities, should be squarely in the purview of primary care clinicians and not necessarily referred out for specialty care.  The authors do introduce, as they say, some “intentional vagueness” in this area by stating that “the AAP acknowledges that some primary care clinicians might not be confident of their ability to successfully diagnose and treat ADHD in a child because of the child’s age, coexisting conditions, or other concerns. At any point at which a clinician feels that he or she is not adequately trained or is uncertain about making a diagnosis or continuing with treatment, a referral to a pediatric or mental health subspecialist should be made (pg5).”  However, the sentence’s inclusion of potential reasons a referral would need to be made suggests that typically presenting ADHD would generally be expected to be handled in house. 

Such a position has met some criticism from different angles, including a few within the psychiatric community who keep to the idea that ADHD, especially preschool ADHD, is beyond the limit of most primary care clinicians.  In the article, the AAP acknowledges that the handling even of the initial assessment and management of ADHD would often require significant changes to most practices.  The article refers readers to an AAP toolkit that is available and free to AAP members. 

From my vantage point as a child psychiatrist who has reviewed close to 5000 consultation requests from the area to our outpatient clinic, it is clear that there is a tremendous amount of variability in the amount of workup that is done before a referral is made.  When it comes to ADHD, we receive requests from pediatricians and family physicians who are asking us to take the very first step at evaluation and treatment, while there are others who ask for help only after they have already made a formal diagnosis and have unsuccessfully tried a number of interventions.  Clinicians will always have different comfort levels with different types of problems.  While some variability will always and probably should always exist, does our community need to do more to a) encourage and empower more primary care clinicians to try to take on ADHD themselves in a comprehensive way, b) spend its efforts on recruiting and retaining more mental health professionals to take on the task, or c) both? 

Reference 

Wolraich, M., Brown, L., Brown, R. T., DuPaul, G., Earls, M., Feldman, H. M., et al. (2011). ADHD: clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics, 128(5), 1007-1022.

Sensory Over-Responsiveness and Psychiatric Disorders

Posted: February 29th, 2012 by David Rettew

Sensory Over-Responsiveness and Psychiatric Disorders

by John Koutras, MD

A new study sheds light on the link between children who are hypersensitive to sounds, textures, etc. and the presence of psychiatric disorders.   This condition has been termed sensory over-responsivity (SOR), or difficulties in sensory integration.  While the presence of SOR can clinically be a red flag for the presence of psychopathology, no study has systematically analyzed the degree to which SOR is distinct from various psychiatric disorders.   This twin study of school-age children also had the advantage of being able to test for shared genetic and environmental influences between the two areas. 

Primary caregivers were interviewed using the Diagnostic Interview Schedule for Children (DISC), offering probable diagnoses.  Of note, however, autistic spectrum disorders were excluded.  Symptoms of over-responsivity were obtained by parent interviews with the SensOR interview, which assesses both auditory symptoms (such as toilet flushing sounds) and tactile symptoms (such as finger paint). 

Approximately 58% of children with SOR met criteria for a psychiatric disorder.  This number dropped to 42% if Specific Phobia was excluded. Thus, a substantial portion of children who screened positive for SOR do not have a formal diagnosis, although there was overlap.  There was evidence of shared genes influencing both SOR and particularly internalizing symptoms like depression and anxiety.

Reference:  Van Hulle C, Schmidt N, et al.  Is sensory over-responsivity distinguishable from childhood behavior problems?  A phenotypic and genetic analysis.  J Child Psychology and Psychiatry 2012: 53 Jan: 64-72.

Vermont Youth are Taking Fewer Psychiatric Medications

Posted: February 21st, 2012 by David Rettew

At a recent meeting of the state’s Psychopharmacology Trend Monitoring Group, of which I am a member, data was presented from the Department of Vermont Health Access that showed clear reductions over the last three years in the number of Vermont children taking psychiatric medications.  

The data were compiled from children and adolescents who use Medicaid for their insurance.  There were robust drops in most all classes of medications including ADHD medications, antidepressants, and antipsychotic medications.  For example, the percentage of children not in foster care taking antipsychotic medications dropped 61%, 51%, and 47% in the 3-5, 6-10, and 13-17 year age groups from 2009 to 2011.  Antipsychotic use for those in foster care dropped more modestly.  Antidepressants and ADHD medications showed reductions generally around 20-40% in these age groups.  

The one medication that clearly bucked the trend was the over the counter sleep aid melatonin which in some age groups showed increases of more than 100% from 2009. 

What has led to the decrease isn’t clear.  Those of us here at the Vermont Center for Children, Youth and Families would love to take some of the credit in our efforts to be conservative with psychiatric medications both in our own practice and in our recommendations to others (like during our conference Child Psychiatry in Primary Care), but it is likely that many factors are at play.  Increased awareness by primary care physicians of the downsides of agents like antipsychotics may be leading to less comfort prescribing them on their own or without the fairly extensive lab tests that are recommended. 

While I tend to take these data as generally good news, it is impossible to estimate from these data alone the extent to which the trends may also indicate that youth who should appropriately be getting pharmacotherapy are being denied access.  In the end, the challenge for our state continues to be to ensure that children who should be using medications as a part of their treatment plan can get access to them while championing nonpharmacological options to the fullest extent possible.

Tips to Help Against Youth Suicide and Depression

Posted: February 13th, 2012 by David Rettew

The recent tragedy surrounding the attempted suicide in Walpole NH reminds us all that the danger of youth suicide remains active in our own backyard.  Drawing upon the recently blogged Vermont Youth Suicide Prevention Platform and the new website http://www.umatterucanhelp.com , it is worth thinking again about some suggestions for parents and primary care clinicians. 

Tips for Parents

  • Just ask about it.  This sounds simple, but many youth will tell you how they feel if they feel the question is coming from genuine concern.
  • Know the warning signs that indicate the possibility of a child that is seriously depressed and may be contemplating suicide
  • Know some of the triggers that can cause depressed youth to act upon their thoughts.  Relationship problems, bullying, and substance use can all increase the risk.
  • Offer hope.  While expressions like “cheer up” or “smile” can be counterproductive, it can be useful to help your child see that they can get through this difficult time and are loved by many people around them.
  • Encourage your child and adolescent in health promotion activities that improve mood.  Offer to do some of these things with them.
  • Encourage your child to speak to a responsible adult if they have any concern that a friend or peer may be thinking of suicide.  It could literally save their life.
  • If concerned about your child’s safety, take steps to make lethal means of suicide unavailable.
  • Do not leave acutely suicidal individuals alone.
  • Seek professional help if you have any concerns about depression or suicide.

 Tips for Primary Care Clinicians (other than above)

  • Take a moment and contemplate your own personal thoughts about depression and suicide and how those attitudes may be influencing your clinical practice.
  • Take stock of what mental health resources are available to you now.
  • Work with the reality that child psychiatrists and many good evidence-based psychotherapists are in very short supply around here.  A “refer and check-in” strategy may result in a long delay of further action, and you may want to consider additional assessment and interim treatment plans.   
  • Check-in with how parents and other family members are doing.  Sometimes the intensity of a suicidal youth causes other important family issues to be neglected.
  • Strive to be as knowledgeable and comfortable about pediatric depression as possible (in addition to the million other things you are expected to know well).
  • Be an advocate to help Vermonters get the help and resources they need.

 The suffering of pediatric depression can often be alleviated and many youth suicides can be prevented with a coordinated and comprehensive approach.

New Program for Vermont Youth Suicide Prevention

Posted: February 7th, 2012 by David Rettew

The Vermont Youth Suicide Prevention Platform 2012 was released yesterday by the Center for Health and Learning.  This program is developed from a grant awarded to the Center from SAMHSA and features 10 specific components, including a new website http://www.umatterucangethelp.com/ designed for youth to access themselves to get important information of what to do if they or someone they know may be at risk for suicide. 

 The full program, published in a user friendly and practical format, can be downloaded from the Center’s website here.  

In reviewing the documents, much of the emphasis appears to be on public awareness and screening procedures.  There are also important efforts to reduce access to lethal means and help various media outlets cover youth suicides without increasing the risk of contagion.  Such initiatives add important dimensions to standard suicide prevention endeavors.  

My only concern of the program might be a relative over-emphasis on identification of at-risk individuals and a relative under-emphasis on how to intervene effectively once these youth have been identified.  With access to mental health professionals trained in evidence-based treatment of youth depression and suicidal behavior still incredibly in short supply, it is very possible that we will encounter a very unsettling bottleneck of identified youth needing services with no place to go.

Are You Under Dosing SSRIs?

Posted: February 6th, 2012 by David Rettew

At a recent pharmacology update sponsored by the American Academy of Child and Adolescent Psychiatry, John Walkup MD, vice chair of child and adolescent psychiatry at the Presbyterian Hospital/Weill Cornell Medical Center. He stated that using a subtherapeutic dose continues to stigmatize children for being on medications and having continued symptoms while not getting the benefit of the treatment.  Dr. Walkup was a principle investigator of a large clinical trial of sertraline in pediatric anxiety disorders that appeared in the New England Journal of Medicine in 2008.  The average daily dose of sertraline in that study was 134mg and was generally well tolerated.   Many patients responded to sertraline alone (55%), cognitive behavior therapy alone (60%), and especially to the combination (81%).  

This story first appeared in Clinical Psychiatry News.

In addition to many residual symptoms, the practice of using too low of a dose can lead to physicians and families believing that a medication is ineffective when it may not be, which in turn can lead to frequent switching of agents. 

It is quite reasonable to attempt to treat many children and adolescents with mood and anxiety disorders first with a trial of cognitive-behavioral therapy.  If pharmacologic treatment is indicated, however, physicians should consider titrating the dose upwards if a patient has not had a robust response at a lower dose for an extended period of time (at least a month).   During that interim period, it can be very useful to discuss with the family other nonpharmacological interventions for anxiety including exercise, mindfulness practices, and even listening to classical music.

Physicians should also be aware, however,  that SSRIs can sometimes lead to worsening symptoms of irritability, so a good review of how dose is related to symptoms can be very useful.  In addition, new cardiac warnings have been released for higher doses of citalopram and escitalopram.

Sleeping Problems in Children

Posted: January 31st, 2012 by David Rettew

Chronic sleep problems put kids at increased risk for behavioral problems, attentional difficulties and even obesity.  The amount of sleep a child needs is variable and generally depends on the child’s age.  The National Sleep Foundation reports that, on average, children need to following amount of sleep.

Below 12 months of age:  more than 14 hours per day

1-3 years:  12-14 hours per day

3-5 years:  11-13 hours per day

5-12 year:  10-11 hours per day

Adolescents: 8-10 hours per day

Many children have trouble getting or staying asleep and more and more parents are turning to medications and over-the-counter pills such as melatonin.  While some studies show that they are generally safe and effective in the short term, their long term safety has not been established and many parents report that they lose their efficacy over time, resulting in higher doses or switches to more powerful agents. 

Before considering this path, it is worthwhile to check in with families about sleep hygiene.  Of particular significance to children are the following items that can markedly improve sleep without resorting to pills. 

  • Exercise.  Kids weren’t designed to sit around on the couch all day, and parents shouldn’t be surprised when more sedentary children don’t feel tired at night.  Encourage families to start early in enforcing regular exercise and limits on television and video games.
  • Caffeine.  Most parents know about coffee and cola, but caffeine can be found in many other food products from chocolate to other types of soda.  These items can make it very difficult to fall asleep.
  • Bedtime routines.  While a slightly later bedtime at night on weekends and vacations is probably okay, most kids get to sleep better when their bedtime is consistent and part of a nightly routine.
  • Sleeping environment.  Keep TVs and computers out of child bedrooms, and have good shades on the windows.  Temperature, noise, and the mattress can all play a role in making an optimal environment for sleep.

 In the primary care office, a couple other situations are also worth mentioning.

  • In working with a family trying to wean off a sleeping pill, it can be very useful to instruct them to begin tapering on days that the child might be extra tired (like after a big soccer game).  Also, it can be very important to help parents anticipate that sleep might first get worse before it gets better when stopping or reducing a sleep agent.  This anticipation can help them not give up too quickly.
  • In working up ADHD or depression, take time to investigate sleep.  For some children, the sleep problems are a result of the underlying condition, but for others it may be more of a cause of the symptoms.
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